On September 14, 1990, an operation called gene therapy was successfully carried out at the United States National Institutes of Health. The operation was only a temporary success as many problems have arisen since then. Gene therapy is a remedy that introduces genes into target cells and replaces defective genes to cure diseases that cannot be cured by traditional medicines. Although gene therapy gives someone who is born with a genetic disease or suffers from cancer a permanent chance at being cured, it is high risk and sometimes unethical because the failure rate is extremely high and issues such as how “good” and “bad” uses are addressed. The questions of gene therapy have still not been satisfactorily answered. Gene therapy gives people with genetic diseases a chance to lead a normal life. Dangerous diseases, such as AIDS, SCID, thalassemia and ADA, can be successfully cured. On September 5, 2006, two people with advanced melanoma received gene therapy and quickly recovered. This is a major advance in cancer gene therapy. Gene therapy uses patients' own cells to cure diseases and, therefore, no rejection in their body. Additionally, patients could achieve a permanent cure through gene therapy without recurrence. Although gene therapy is magical, it comes with high risk. Few people have benefited from it and the success rate is low. Before the human trial, Batshaw and Wilson had conducted animal experiments to ensure safety. More than 20 experiments were performed on mice, but only 12 of them ultimately survived (Sophia, M. and Kolehmainen, JD, 2000). Even more serious, complicated diseases, which may be more dangerous than genetic diseases, could arise during the treatment period. In December 200...... middle of paper ......s of gene therapy is that the mortality rate is very high. This is because the immune system can attack cells and cells can attack vital organs. Furthermore, ethical issues should be addressed in a positive manner. The technological institute must reduce unnecessary expenses of treatment. I strongly suggest that the government invest more money in the development of gene therapy. In conclusion, although gene therapy can cure a wide variety of diseases that cannot be cured by traditional medicine and patients can achieve permanent cure without rejection, it can be high. risky and immoral. The negative effects of gene therapy are leading to fewer volunteers and many trials have been forced to be halted. The potential for gene therapy to revolutionize medicine in the future is exciting and hopes are high for its role in curing and preventing childhood diseases..