Abstract The current study illustrates the important roles and applications of bioinformatics, proteomics and genomics in biotechnology. The study clearly describes that bioinformatics, proteomics and genomics play important roles in drug discovery and design, agriculture, development of personalized drugs, biomarkers and many other areas which will be very useful in current and future generations of living organisms. Finally, the study also highlights some points from recent studies on bioinformatics, proteomics and genomics carried out by other researchers and their future capabilities are also clearly mentioned.1. IntroductionBiotechnology can be generally defined as the discipline that uses living organisms or their products for profitable purposes. It is not just an individual technology but rather a combination of technologies that contribute to two general characteristics that work with living cells and their molecules and have a variety of practical uses that can improve our lives (Dunnill P., 1981). .2. Definition of BioinformaticsBioinformatics is a discipline that is a mixture of molecular biology and computer science. In this field, computers are used to assemble, accumulate, analyze and incorporate biological and genetic information about living organisms. The need for bioinformatics emerged when the project to discover the sequence of the entire human genome was launched (Chris S., 2003). This project was known as the “Human Genome Project”. This topic is considered very important for the use of genetic information to learn about human diseases and recognize new approaches in the middle of the article......migration to normal recipient cells occurs. 5. ConclusionFrom the study it can be concluded that the methodologies involved in bioinformatics, proteomics and genomics have many applications in biotechnology and the techniques involved in these areas can be used to discover new drugs, understand the functions of genes responsible for cancer, thus this to develop therapeutic drugs in future and furthermore, the study showed that with the improvement of technologies related to these areas, many challenges such as developing an accurate drug for prostate cancer and effective prediction of 3D protein structure can be clearly solved. . The information from the study clearly describes that bioinformatics, proteomics and genomics have great potential, now and in the future, if enhanced appropriately..